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It is a well-known fact that cigarettes are harmful to humans

8 Another study found that smokers homes contained THS even 6 months after they stopped smoking

Unsmoked filters were obtained from commercially available cigarettes ( L&M Blue Label cigarettes) and incorporated to investigate the toxicity of substances originally present in virgin filters

54 Isoprene, present in the gases of tobacco emissions, causes cancer in mice and rats, 55 , 56 and may cause lung cancer in smokers

Conclusions There is evidence showing a reduction in the concentration of serum levels of fluvoxamine, duloxetine, mirtazapine and trazodone in smoking patients as compared to nonsmokers